Searchable abstracts of presentations at key conferences in endocrinology

ea0041oc8.2 | Thyroid - Translational | ECE2016

Selenium modulates apoptosis in thyroid follicular cells: characterization of molecular mechanisms

Cristina Nettore Immacolata , Maione Luigi , Passaro Carmela , Pivonello Claudia , Negri Mariarosaria , Desiderio Silvio , De Nisco Emma , Pivonello Rosario , Ungaro Paola , Portella Giuseppe , Colao Annamaria , Emidio Macchia Paolo

: Inflammation and several oxidative processes are modulated by Selenium (Se) trough the selenoproteins. Se deficiency has been associated with thyroid autoimmune diseases and hypothyroidism, while Se-supplementation reduces antibodies titles and ameliorates ultrasound pattern of the gland.Aim of the current study, is to study the molecular effects of Se-supplementation in thyroid follicular cells (FRTL5).FRTL5 cells have been star...